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Blood Spot - Vitamin D Blood Spot

Doctors DataSKU: A2836

25-Hydroxyvitamin D, known for its role in bone health and calcium absorption, also appears to affect immune function, neurodegenerative and cardiovascular issues, and other conditions. Vitamin D occurs in two forms—D3 is obtained from animal diet sources and through sun exposure, and D2 is obtained through vegetable diet sources. Both forms of the vitamin are used to fortify various foods...

Full Description

This test is useful for

  • Alzheimer's Disease
  • Bone Health
  • Calcium Absorption
  • Cardiovascular Disease
  • Depression
  • Immune Function
  • Infections
  • Multiple Sclerosis
  • Neurocognitive Dysfunction
  • Preeclampsia
  • Rheumatoid Arthritis
  • Type 2 Diabetes

Find out more

  • View Sample Report
  • Please contact us at (714) 864-3730 or to order your test.

Blood Spot

Blood spot testing is very easy to collect, utilizes a simple finger prick collection system that can be conveniently performed at home by the patient, and does not require a venous blood draw or phlebotomist. Blood spot stability and integrity is maintained through desiccation, and samples can be mailed from anywhere in the world in a prepaid return envelope that does not require an express courier. The experienced staff at Doctor’s Data has validated many different tests using this collection method, and correlation data between blood spot and serum/blood samples is available for each assay.

Detailed Information

25-Hydroxyvitamin D is the major circulating form of vitamin D. It occurs in two forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), and is the precursor of the active form (1,25-dihydroxyvitamin D). Because of its long half-life, measurement of total 25-Hydroxyvitamin D (D2 plus D3) provides the best assessment of patient vitamin D status and includes vitamin D derived from diet, supplements and exposure to UVB light, such as sunlight. Vitamin D is best known for its role in calcium and bone metabolism, but emerging research indicates that low levels of vitamin D may be associated with increased risk of some cancers, type 2 diabetes, multiple sclerosis, cardiovascular disease, rheumatoid arthritis, depression, Alzheimer's disease, infections, preeclampsia, cesarean deliveries and neurocognitive dysfunction. Vitamin D regulates the expression of a vast array of genes in tissues including immune cells, the vasculature, muscle and reproductive organs. Vitamin D insufficiency is common and deficiency can have adverse health effects at any stage of life. Many testing methods do not differentiate between the two forms of vitamin D, and only total concentrations are reported. This LC/MS QQQ method is sensitive and specific for both vitamin D2 and D3, and each form is measured and reported independently.

Usage Directions

Before you start:

Please read all of the directions, and familiarize yourself with the collection procedures.

This test requires no special diet. Discuss with your healthcare provider if you are taking blood thinning medications or if you have a blood clotting disorder. Never discontinue prescription medications without first consulting your physician.

The lancets and collection card provided are for one time use only. Do not collect from the fifth/little finger, or on children younger than one year, because the tissue depth is insufficient. Do not layer blood on a previously dried spot. Avoid strong repetitive pressure (milking) in the pricked finger. This may cause tissue-fluid contamination of the specimen.

More Instructions:

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