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Gamma-amino butyric acid (GABA) is one of the major inhibitory neurotransmitters in the brain. GABA provides a calming effect and is a primary component of the body’s stress-fighting mechanisms. Cerenity includes a patented, naturally-sourced, non-synthetic form of GABA called PharmaGABATM. It is produced naturally by the friendly bacteria, Lactobacillus hilgardii. In contrast to synthetic GABA sources, PharmaGABATM has been shown in published research studies to promote a state of relaxation.
Inositol is a B vitamin that is an important component of cell membrane signaling. As part of the cellular signaling system of the central nervous system, inositol is crucial for the release of neurotransmitters from within the nerve cells.
Taurine is an amino acid that is found abundantly in the brain and has neuroprotective properties.
5-hydroxytryptophan (5-HTP) is an amino acid intermediate that is directly converted into the mood-regulating neurotransmitter serotonin.
Cerenity includes essential nutrients that are required for the synthesis of serotonin and GABA neurotransmitters. This includes 5-methyltetrahydrofolate (5-MTHF), vitamin B6 (P-5-P), vitamin C, zinc and magnesium.
L-theanine is an amino acid found abundantly in green tea. L-theanine has been shown to quickly improve stress perception and resilience. The stress-buffering mechanisms of L-theanine have been connected to the ability of L-theanine to increase serotonin and dopamine production in the brain. L-theanine has also been shown to significantly increase alpha brain wave activity, which is critical for increasing attention as well as promoting a sense of relaxation. L-theanine has also been shown to have a protective effect for nerve cells and reduces excitatory glutamate activity in the brain.
Phosphatidylserine is a phospholipid that is found in high concentrations in the brain. In studies administering phosphatidylserine (50-800 mg) to subjects under stress (physical, emotional, mental, etc.), it has been found that phosphatidylserine reduces stress-induced excretion of cortisol. Administration of phosphatidylserine has also been studied in exercising subjects. It has been demonstrated that phosphatidylserine reduces the cortisol response to overtraining resulting in a reduction in perceived muscle soreness and improvement in athletic performance.
Bacopa monierri is an herb that provides nervous system support for individuals under stress. Bacognize® is known to improve memory, learning, attention, and focus. It is shown to have strong regulation of mood function at the serotonin receptor. Bacopa offers neuroprotection and antioxidant effects to reduce oxidative stress.
Ashwagandha Root Extract
Ashwagandha’s strong adaptogenic properties provide an array of benefits for individuals that have compromised health due to extreme stress exposure. Ashwagandha’s benefits include improving stress resilience, supporting immune response, regulating the sleep cycle, supporting healthy thyroid function and protecting against exhaustion of the nervous system. Ashwagandha has also been shown to be beneficial in supporting proper mood regulation and restoring a sense of calmness under stress.
Rhodiola rosea Root Extract
Rhodiola rosea has been categorized as an adaptogenic botanical due to its ability to increase resistance to a variety of stressors. Rhodiola has been studied extensively and is widely used in Eastern Europe and Asia to help support the nervous system, mood regulation, mental clarity, work performance and the sleep cycle. Within the central nervous system, Rhodiola has demonstrated an ability to preserve levels of neurotransmitters such as serotonin, dopamine and norepinephrine. Rhodiola has been examined for its significant reduction of fatigue under stress. It has also shown significant improvements in mental performance, greater mood stability, and improved sleep patterns.
Eleuthero Root Extract
Eleutherococcus senticosus has also been identified as a strong adaptogenic botanical and is widely used in China to improve general health, support memory and endurance. In addition to its ability to improve stress resilience and fight fatigue, Eleuthero has exhibited immune supporting effects. Eleuthero has demonstrated a reduction of heart rate in response to a stressor and improvement of performance in runners (race time).