Gastrointestinal Health - Zonulin Family Protein, stool
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Clinical microbiology plays a crucial role in individual and community health. Because most microbes living on or within the body are beneficial, distinguishing those that are disease-producing is a critical function of a clinical microbiology laboratory.
Doctor's Data bridges traditional clinical microbiology with complementary medicine, providing world-class diagnostic microbiology testing that helps you assess digestive and absorptive functions, detect pathogens or parasites and identify specific bacteria and yeast. Through specimens collected from a variety of body sites and the use of advanced assays and technology, Doctor's Data determines what microorganisms are present and which may be causing infection. Our painstaking approach can help you select the most appropriate antimicrobial therapy and the comprehensive nature of our testing represents real value for your patients and practice.
Elevated fecal levels of ZFP have been associated with metabolic syndrome, obesity, and apparently healthy cigarette smokers. High serum levels of ZFP (antigen) are correlated with abnormal results of the Lactulose Mannitol test; the long-accepted standard for intestinal permeability, but to date no such correlation has been reported with fecal ZFP. Excessive intake of simple sugars, sodium, emulsifiers, microbial transglutaminase (food additive) and nano-particles may also be triggers for increased fecal ZFP and intestinal permeability. Possible interventions to restore the gastrointestinal mucosal barrier include dietary changes, treatment of dysbiosis, digestive supports and anti-inflammatory supplements; specifically quercetin, vitamin C, curcumin, gamma-linoleic acid, omega-3 fatty acids (EPA, DHA), and aloe vera. Other nutrients such as zinc, beta-carotene, pantothenic acid, and L-glutamine may provide some support for rejuvenation of the mucosal barrier. The use of some probiotics has been shown to reduce serum and fecal zonulin levels, and inulin (about 10 grams per day) lowered serum zonulin after just five days in healthy young subjects. Consider a Comprehensive Stool Analysis to further investigate potential causes of increased intestinal permeability.
- Zonulin Family Protein; stool
Before You Start:
Please read all of the directions, and familiarize yourself with the collection procedures. If you are taking antifungal or antibiotic medications, please finish the course of medication, and then wait three days before starting this collection. Please refrain from taking digestive enzymes, antacids, and aspirin for two days prior to and during the specimen collection, unless otherwise instructed by your physician. Never discontinue prescription medications without first consulting your physician.
Collection Instructions: here