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The discovery that the gut barrier plays a key role in immune health fueled the search to strengthen it. In that search, researchers found that the binding capabilities of immunoglobulins have a positive effect on gut barrier function. Immunoglobulins bind microbes and toxins in the GI tract and eliminate them prior to immune system activation. As these unwanted triggers are removed, it resets healthy immune tolerance and builds a stronger barrier to the external environment.
SBI and GI Health
SBI has been shown to bind microbes and toxins, further enhancing microbiome balance and facilitating gut barrier strength. Broad-spectrum binding capabilities demonstrate the positive influence of non-allergenic forms of immunoglobulins. As seen in several studies, SBI has the potential to bind many types of microbes and toxins. This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance.
SBI and Immune Health
In studies evaluating the effect of SBI on immune function, subjects showed positive outcomes in several areas, including inflammatory balance, gut barrier function and immune cell counts. In an open-label human clinical study, GI-challenged patients were given 2.5 mg SBI twice daily. They had increased CD4+ counts in the duodenum after eight weeks, indicating a regenerative effect on the tissue and immune function in the intestines.
The purpose of the epithelium is to allow the digestion and absorption of dietary nutrients while keeping unwanted toxins, microbes and food particles from passing directly into the body. GlutaShield includes a high dose of L-glutamine (4 g), which serves as nutrition for the gut lining. It provides 400 mg of deglycyrrhized licorice root extract (DGL) and 75 mg of aloe vera extract, both of which protect and promote the health of the gut mucosa. N-acetyl glucosamine and zinc boost GI integrity. GlutaShield is available in delicious chocolate and vanilla flavors.
Deglycyrrhized Licorice Root Extract (DGL)
DGL is a form of licorice root that has been specially processed to contain only biologically active flavonoids, without glycyrrhizin. This allows for higher dosing of the active ingredient, which helps maintain a healthy mucosal surface.
Aloe Vera Leaf Gel Extract
A demulcent that has been used throughout history, aloe vera has long been known to maintain normal inflammatory balance.
L-glutamine is a main source of fuel for the cells of the small intestines and essential to tissue repair throughout the body.
N-acetyl glucosamine is the acetylated form of glucosamine. It is a mucin precursor and has been shown to increase the production of mucus within the GI tract.
Zinc is an essential mineral widely recognized for its role in gut and immune health. Zinc has been shown to strengthen GI barrier function by supporting the structure of tight junctions.
Going beyond the threshold of traditional probiotic support, high-dose probiotics influence gut health and immunity in ways lower-dose probiotics cannot. Shown to activate over 1,700 genes involved in immune and inflammatory signaling, high-dose probiotics support a healthy, balanced immune response. Delivering 225 billion active probiotic cultures per packet, Probiotic 225 creates a rapid response to reset the immune system and maintain normal inflammatory balance. Each convenient, single serving packet provides six proven strains chosen for their ability to survive the harsh GI environment and deliver superior results.
Lactobacillus acidophilus (La-14)
Lactobacillus acidophilus is a beneficial bacteria strain that is normally found in the intestinal tract and mouth, and is commercially used in dairy products for the production of acidophilus-type yogurt. L. acidophilus ferments various carbohydrates to produce lactic acid, which increases the absorption and bioavailability of minerals, including calcium, copper, magnesium and manganese.
Lactobacillus plantarum (Lp-115)
Lactobacillus plantarum is beneficial bacteria commonly found in fermented foods including sauerkraut, pickles, brined olives and sourdough. L. plantarum has been found to compete against strains of Clostridium difficile and Clostridium perfringens, due to the production of bacteriocins (lethal proteins) that inhibit bacterial growth.
Bifidobacterium lactis (BI-04)
Bifidobacterium lactis is predominantly found in the colon. A double-blind, randomized placebo-controlled trial on subjects receiving B. lactis or placebo for eight weeks found that B. lactis supported a balanced immune response in individuals hypersensitive to environmental allergens.
Lactobacillus salivarius (Ls-33)
Lactobacillus salivarius has been shown to produce bacteriocins, which inhibit the growth of Helicobacter pylori.
Lactobacillus casei (Lc-11)
The immune-regulating properties of Lactobacillus casei have been reported in several studies. L. casei has been shown to regulate inflammatory pathways and reduce oxidative stress.
Bifidobacterium bifidum (Bb-02)
Bifidobacterium bifidum has been shown to effectively compete with harmful bacteria such as E. coli, Staphyolococcus aureus and Camplylobacter jejuni.
Larch arabinogalactan is a fermentable polysaccharide fiber from the larch tree that enhances immunity by supporting the growth of beneficial gut microflora and strengthening the activity of NK cells.